Principal Scientist or Senior Scientist, NBE Pharmacokinetics

Recruiter
Boehringer Ingelheim
Location
Ridgefield
Salary
Competitive
Posted
Oct 10, 2016
Closes
Oct 19, 2016
Role
Research
Industry
Education
Employer Type
Direct Employer
Employment Type
Permanent
Hours
Full Time
Description:

Description\:
Qualified candidate to be hired at the level commensurate with education/experience.


Design and implement mechanistic PK/PD and quantitative systems pharmacology models in support of pre-clinical NBE R&D projects. Represent the PK/PD modeling discipline on multi-disciplinary teams and integrate PK/PD considerations into team strategy. Collaborate with key stakeholders in pre-clinical and clinical development in support of the overall translational research strategy for projects. Enhance capabilities of group by implementing novel modeling approaches and technologies.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities\:
  • Independently develops pre-clinical PK/PD and quantitative systems pharmacology models that enhance decision making and inform translational research strategy for NBEs
  • Uses modeling and simulation to predict human efficacious dose/dose regimen, and influences selection of first-in-human starting dose
  • Designs, analyzes and interprets data and communicates results to teams and management
  • Leverages literature data or proposes new experiments to validate models or test model-generated hypotheses
  • Develops new methodologies, protocols or procedures that contribute to core group/research goals and reflect expert knowledge
  • PK/PD modeling representative on multiple cross-functional project teams
  • Effectively collaborates with scientists within and outside functional area
  • Prepares clear technical reports, publications and oral presentations
  • Develops broad knowledge in field of expertise and enhances internal capabilities of group
  • Presents work at internal/external scientific meetings and publishes work in scientific journals
Requirements for Senior Scientist\:
  • Ph.D. Degree (biology, physiology, pharmacology, chemistry pharmacokinetics, pharmacy, pharmaceutical sciences or related field) or equivalent experience in a related field
  • Demonstrates a broad knowledge of field (electrophysiology, pharmacology, physiology, pharmacokinetics, pharmacodynamics or pharmaceutics)
  • Appropriate level of understanding of applicable regulations
  • Ability to communicate effectively both orally and in writing in an inter disciplinary environment Ph.D. or equivalent experience in a related field
  • Theoretical and practical knowledge of pharmacokinetics, PK/PD and quantitative systems pharmacology modeling
  • Experience using one or more commercially available modeling and simulation platforms (e.g. Phoenix/WinNonlin, ADAPT, NONMEM, MATLAB, SimBiology, etc.)
  • Experience in mechanism-based PK/PD modeling of therapeutic proteins is highly desired
  • Ability to build and maintain effective working relationships inside and outside department
  • Strong aptitude for working with cross-functional and global teams
  • Ability to communicate effectively both orally and in writing in an interdisciplinary environment
Requirements for Principal Scientist\:
  • Ph.D. Degree (biology, physiology, pharmacology, chemistry, pharmacokinetics,pharmacy, pharmaceutical sciences or related field) with 5 + years experience in a related scientific discipline or equivalent experience in a related field.
  • Previous supervisory experience preferred
  • Demonstrates a broad knowledge of field (electrophysiology, pharmacology, physiology, pharmacokinetics, pharmacodynamics or pharmaceutics)
  • Appropriate level of understanding of applicable regulations
  • Ability to communicate effectively both orally and in writing in an interdisciplinary environment
  • Theoretical and practical knowledge of pharmocokinetics, PK/PD and quantitative systems pharmacology modeling
  • Experience using one or more commercially available modeling and simulation platforms (e.g.Phoenix/WinNolin, ADAPT, NONMEM, MATLAB, SimBiology, etc.)
  • Experience in mechanism-based PK/PD modeling of therapeutic proteins is highly desired
  • Ability to build and maintain effective working relationships inside and outside department
  • Strong aptitude for working with cross-functional and global teams

Eligibility Requirements\:
  • Must be legally authorized to work in the United States
  • Must be willing to submit to a background investigation, including verification of your past employment, criminal history, and educational background
  • Must be 18 years of age or older
Our Culture\:
Boehringer Ingelheim is a different kind of pharmaceutical company, a privately held company with the ability to have an innovative and long term view. Our focus is on scientific discoveries that improve patients' lives and we equate success as a pharmaceutical company with the steady introduction of truly innovative medicines. Boehringer Ingelheim is the largest privately held pharmaceutical corporation in the world and ranks among the world's 20 leading pharmaceutical corporations. At Boehringer Ingelheim, we are committed to delivering value through innovation. Employees are challenged to take initiative and achieve outstanding results. Ultimately, our culture and drive allows us to maintain one of the highest levels of excellence in our industry. Boehringer Ingelheim, including Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim USA, Boehringer Ingelheim Roxane Inc., Roxane Laboratories Inc., Boehringer Ingelheim Chemicals, Boehringer Ingelheim Vetmedica Inc. and Ben Venue Laboratories Inc., is an equal opportunity employer. M/F/D/V
Boehringer Ingelheim is firmly committed to ensuring a safe, healthy, productive and efficient work environment for our employees, partners and customers.

*LI-DS1

*I-DS1